Banishes Wrinkles and Improves Sun Damaged-Aging Skin

The protein collagen is the main structural component of the dermis. Aging skin can often appear dry, lax, and wrinkled as a result of damaged collagen. Collagen is regulated by a multitude of factors that can basically be grouped into processes and biochemicals that promote the synthesis of collagen or those that induce its degradation.95

Research conducted on human cell lines demonstrated that astragalus promotes the production of hyaluronic acid (HA), which in turn induces growth of collagen-producing cells called fibroblasts.93 HA molecules are an integral part of skin structure. As levels of HA decrease with age the synthesis of collagen is also reduced—resulting in the clinical signs of aging skin. Results of another study indicated that astragalus also directly stimulates collagen production by both young and aged fibroblasts.95

Recently a lab study on extracts from the seeds of Astragalus sinicus has also demonstrated some promising anti-aging skin effects different than other species of astragalus. At concentration levels of 200 µg/mL, A. sinicus extracts inhibited the enzyme that breaks down elastin—another component of skin that lends to its youthful appearance and texture—by 97.5%. And at 300 µg/mL, it inhibited the enzyme that breaks down collagen by 99%. Results of an 8-week clinical trial to follow up on these remarkable lab results using a topical cream containing 20% of A. sinicus extract suggest that it may be useful in improving the texture, elasticity, and tone of skin.24

These preliminary studies suggest that astragalus may have a role in skin care products that counteract wrinkles and sagging skin caused by age-related decreases in collagen.

Both Astragalus membranaceus and Astragalus mongholicus.
Middle layer of the skin.
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